分类归档 sports

2023 is the year of recovery, but it will not reproduce the "madness" of 2019.

Text | Caijing reporter Zhao Tianyu Ling Xin

Edit | Wang Xiao

"There are several interesting projects. Once New Year’s Day is over, the negotiations will go smoothly." Zhang Chen, a partner of Probe Capital, said.

In 2023, many investors who pay attention to the medical and health field found that things began to develop in a good direction. According to the incomplete statistics of Caijing reporters, the opening year is only one month, and as of February 6, the total number of medical and health investment and financing has exceeded 50.

Together with Zhang Chen, many investors are willing to believe that the first half of 2023 will definitely increase, and it will be good, and the secondary market will be good.

Sequoia China predicted that,Investment and financing behavior will accelerate in 2023, because some investors feel that the market price has been adjusted back to a certain stage and are considering whether it is time to take the shot.

In the medical and health industry, what opportunities will appear in 2023?

"Oncolytic virus is a hot spot this year." In early January, Tang Haofu, a partner of Shanghai Chuangrui Fund and Chongqing Dianshi Chuangjian Fund, went to San Francisco to attend the J.P. Morgan Healthcare Conference in JPMorgan Chase, which was one of the trends he observed. JPMorgan Chase Medical and Health Conference, the largest and most informative medical investment seminar in the world, has become the vane of the global medical and health industry once a year.

Oncolytic virus is a kind of virus that can cause cancer cell apoptosis after being integrated into cancer cells, while keeping normal tissues from being destroyed, and can deal with different types and stages of tumors. After nearly 30 years of verification, it has become an important branch of tumor immunotherapy. In 2015, the US Food and Drug Administration (FDA) approved the marketing of oncolytic virus product Imlygic (T-Vec), which treats melanoma by intratumoral injection.

From the medical and health conference in JPMorgan Chase in 2023, small nucleic acid drugs, adeno-associated virus vectors (AAV) and new drug-carrying technologies of liposomes are also hot directions.

For small molecule drugs and antibody drugs, it will be better to have innovative targets. Although the new use of old drugs in oral medicine in COVID-19 was very successful, only one indication was changed, which was not well received at the meeting.

In the field of cell therapy, the fourth generation CAR-T has attracted much attention and has become the mainstream overseas. As for the targets that many local companies are still doing, such as CAR-T therapy targeting CD19 and CD22, few people abroad have done it.

In Tang Haofu’s view, cytokine storm, the number one risk factor in the clinical application of CAR-T therapy, is expected to be significantly reduced in the next three years. CAR-T therapy is mainly used for tumor treatment. Although this technology can remove tumor cells, it will also produce toxic side effects, that is, cytokine storm, by attacking normal cells in the body.

Tang Haofu looked at some projects and found that everyone was doing it in this direction. For example, Elpis, whose core team is from Harvard Medical School, has reduced its data cytokine storm by more than 70%.

In the field of cell and gene therapy (CGT), in 2023, many investors expressed their continued optimism.

Li Yishi, senior partner of Haoyue Capital, said,Cell therapy drugs, for a period of time, are mostly used for back-line patients, that is, those patients who have been resistant to most existing therapies.

The back-end market is relatively small, so it is unlikely to produce a large variety of drugs with sales of 1 billion yuan.

"If you want to say that there is an opportunity, it has to be this kind-if everyone has an opportunity, it is sunny, is it still an opportunity?" Li Yishi said.

As for gene therapy, Li Yishi said that at present, the whole field is dominated by rare diseases, and going to sea is the main commercial path.

"Gold digger" may not be successful, "water seller" still has a chance, but the field has been very subdivided.Zhang Chen is concerned about the mRNA in the direction of tumors and infectious diseases. He thinks that in this industrial chain, the opportunity of "selling water" is the best, such as making cell culture medium, and then looking further, transfecting reagents.

"We want to find some powerful companies and stay with them all the time. If we serve an infrastructure, it will become a profitable position." Zhang Chen said.

He is also optimistic about the opportunities of proteomics and structural biology. The demand for proteomics is increasing, and the financing in China market is accelerating; The contribution of structural biology to pharmacy may appear in the next year or two, especially the continuation of structural biology based on cryoelectron microscopy.

In terms of innovative instruments, Sequoia China said that it would pay attention to globally synchronized cutting-edge technologies such as single cell sequencing and single molecule protein detection.

Some investors favor gene sequencer. Zhang Chen said,At present, there is still room for improvement in mainstream machines. If the signal and noise can be well distinguished, early tumor screening will be more available. Hospitals require high detection speed, which requires machines with more flexible throughput, and the most important thing is the innovation at the bottom of sequencing.

It has been three years since the epidemic, and the detection in Covid-19 has fluctuated greatly. Both nucleic acid detection and antigen detection are betting on a policy window period, which leads to the concern of IVD (in vitro diagnosis) industry. Zhang Chen said frankly that because he was not sure what products would sell well in the future, he chose to look upstream.

Cardiovascular, neurosurgery, orthopedics and ophthalmology are the departments frequently mentioned by investors.

Although cardiovascular and orthopedics have been targeted by the national centralized procurement, they are still the departments that bring the most cash flow to hospitals, and the consumption of consumables is large and the demand is large, which promotes the emergence of new technologies and materials.

How to make doctors more labor-saving is a big product direction. Zhang Chen pays attention to small active medical devices (plugged in) and hopes that the higher the intelligence and complexity, the better.

Some instruments used in departments such as gastroenterology and cardiology will continue to develop into software and nano-scale miniaturized products. Interventional robots and interventional materials are the highlights.

Tang Haofu observed at the JPMorgan Chase Medical and Health Conference,The interventional robot is taking the route of miniaturization and software, and it is expected that there will be some progress in one or two years. There is also a self-driven gastrointestinal mirror, which is driven by its own propeller, and its technical content is much higher than before.

As for the open surgical robot, it is not a big focus in the short term. The typical product in this field is Da Vinci surgical robot, which consists of three parts: surgeon console, bedside manipulator system and imaging system. By enlarging the field of vision and defibrillating the hand, it helps doctors to complete the operation and reduce the trauma caused by the operation to patients.

Some companies continue to optimize this kind of surgical robot with different structures, but in the eyes of investors, it is "too heavy" and some actions are quite barbaric and not smart enough to operate.

Although surgical robots are not so popular, xenotransplantation, in Tang Haofu’s view, will become a hot investment in two or three years.

In 2022, the Medical College of the University of Maryland transplanted a pig heart to a 57-year-old man. In a few weeks after the operation, the transplanted heart in his body worked well and showed no signs of rejection. It lasted for 63 days until the illness deteriorated and died. This is regarded as a major breakthrough in the field of xenotransplantation, and it is expected that there will be companies mainly engaged in xenotransplantation within two years.

Hou Xuchao, founding partner of Zhuozhi Consulting, proposed that,There are three factors to grasp the opportunity of the industry: breakthrough and development in technology; The market demand and unmet demand are huge; It can improve the performance-to-price ratio or efficiency at some levels.

For 2023, "recovery" is felt by many investors, although the degree is different.

Hou Xuchao believes that on the whole, there will be a great recovery in 2023, but the "madness" in 2019 should not reappear. At present, the overall fund-raising form and exit channels have changed greatly, and the investment strategy and style of private equity funds have also changed greatly, so there will be new local hot spots and explosions, but it will not "raise chickens and dogs to heaven."

Sequoia China observed that,In fact, since October 2022, the biomedical industry has entered a slow recovery process, especially for companies with good fundamentals, and they have also seen many positive improvements.

However, after four years of epidemic tempering, investors’ mentality has become more cautious, the overall investment action has slowed down, and the difficulty of raising funds for companies in the market has also increased.

Li Yishi told Caijing reporter,For the heat of investment and the possibility of financing in 2023, it should be a tentative spiral upward trend.

For the key words in the field of health in 2023, Sequoia China is still an "early investment".

In the past few years, the capital market has made great strides, and the valuations of many primary market companies have soared. For investment institutions, if the investment is not early enough, the multiple of return may decline. From this dimension,In fact, all funds will gradually realize that whether it is active choice or passive choice, it is an inevitable trend to invest early.

Hou Xuchao’s key words are "innovation, efficiency improvement and cost performance". The medical and health field has returned to normal, and the industry continues to emphasize the value of innovation and technology.

Tang Haofu believes that the key word in 2023 is "deep innovation". With the opening of information channels, the communication between investors and overseas countries is getting smoother and smoother, and deep innovation will be valued.

Zhang Chen’s first thought is to consider long-term value, and new technology is the focus.

In Li Yishi’s view, "restart" is the key, and 2023 should be regarded as the first year of real departure after restart.

However, a private equity person in the secondary market said that in the short term of 2023, there are still uncertainties and there is no particularly clear conclusion. In the long run, we are still optimistic about China’s health field, because the problem of aging is more and more prominent, and we spend more on health expenditure.

The resumption of large-scale performances in 2023 not only incited urban cultural tourism, but also became the engine to promote the soaring of many consumer goods industries. From beauty products, hard sunscreen equipment to telephoto lens mobile phones, many single products warmed up in the heat wave of performance economy.

Sales of concert-related industries

This year has soared strongly.

A report on "Performance Economy Explodes and Touches Multi-industry Growth" shows that at the beginning of 2023, large-scale performances were restarted one after another, and the spiritual collision between the audience and artists not only incited urban cultural tourism, but also became the engine to promote the soaring of many consumer goods industries.

According to statistics, more than 400 concerts have been held throughout the country this year, including the peak season in April and May, with nearly 150 concerts per month, which has exceeded the level of the same period in 2019. According to industry estimates, the number of large-scale concerts will exceed 1,000 this year, which will drive the attendance of 6 million to 8 million people.

As of the first half of 2023, the main consumer of the performance market is still young people aged 18 to 39. Among them, the number of female consumers among ticket buyers is significantly higher than that of men, and the proportion of consumers and female consumers after 00 and 95 is increasing year by year. Performance economy is not only a feast of music, but also an important part of young people’s cultural consumption.

With the enthusiastic pursuit of millions of fans and fans, the leverage of the performance economy is constantly rising. According to the data of Amoy Department, the sales of the industry with concerts as the key words have shown a strong soaring trend since January this year. In the first half of the year, the market sales reached its peak twice, which appeared in January and April respectively.

Blending of Fashion and Performance Economy

Make-up wear is concerned

The beauty industry is particularly prominent. In the past three months, the interaction of fashion elements such as makeup and wearing in music festival notes reached 273,600. In the official topic of Little Red Book, the number of views on the topic of "Dressing in Music Festival" in the past 90 days exceeded 50.153 million, and the topic of "Dressing in Music Festival" in the past two months was as high as 75.456 million. Fashion and performance economy have achieved a perfect blend, and the audience not only pursues music, but also swims in the ocean of fashion.

Concert makeup and ribbon braiding, sweet and cool dress make the concert trip more enjoyable; Exquisite and small ornaments shine more brightly in the light, and the spice girls wear them in line with everyone’s enthusiasm, and they instantly get high-performance brokers radiate to many industries. In the content related to the "concert", the social platform has reached the top three in terms of makeup and skin care, clothing and food and drink interaction.

Young people are willing to show their vivid personality, and different concert styles correspond to different makeup. Among the high-profile beauty content related to concerts, bold broken diamond makeup, smoky punk makeup and ghost horse girl makeup have a high appearance rate.

In the volume of makeup, it also shows the characteristics of local refinement. Taking eye makeup as an example, the interaction of "eye shadow" is more prominent. Young people pay special attention to the exquisiteness of each local dress, and want to show a perfect image in offline performances. At the same time, "bright makeup", "no makeup" and "no makeup mottled" have also become key words. After all, in a warm gathering of tens of thousands of people, it is a new demand to keep the makeup intact even if the skin is sweaty and oily.

Record high-definition moments

Telefocal mobile phones become popular items.

Driven by outdoor performances such as music festivals, sunscreen products are also heating up. Especially in the summer when outdoor performances are concentrated, hard sun protection becomes just needed. This year, among the hot words related to the music festival, the hot search index of sun protection clothing and sun protection hat exceeded that of sun protection cream, and sun protection masks, masks, gloves and other items also appeared on the hot search list of sun protection products.

The data can also be seen that the digital field has also been driven to heat up. The popularity of keywords such as "concert shooting artifact" remains high, and fans are keen to discuss which mobile phone has the best shooting performance before watching the performance. The telephoto lens mobile phone has become a hot-selling item. In addition, telescopes originally belonging to the outdoor industry have become hot sellers.

Category, sales in the second quarter of this year also increased significantly.

Under the hot background of performance economy, all related brands have taken advantage of the situation to increase the connection between popular items and popular scenes and actively explore growth points. This not only promoted the prosperity of the performance market, but also produced obvious spillover effects in other industries. From derivatives and cultural and creative products to restaurants and hotels, all of them are booming in the heat wave of performance economy.

Live on May 21st, Bayern lost to Leipzig 1-3 in a key battle at the end of this Bundesliga. The following is a comparison of the specific data of the two sides:

Bayern vs Leipzig

Shooting: 17-14

Straight shot: 5-7

Ball control rate: 60%-40%

Passing success rate: 87%-79%

Foul: 8-11

Yellow card: 1-1

Corner kick: 7-2

(Chenpi is not orange)

The dazzling review of literature and flowers is thousands of miles away.

Typesetting three deer nine

01

"Sugar Bean Man" Linked with "Doraemon" Theater Edition

Recently, "Sugar Bean Man: The Ultimate Elimination" announced that it will launch the theme skin in conjunction with the theatrical animation "Doraemon: Daxiong and the ideal hometown of the sky", which is expected to be installed next season.

Doraemon’s latest theatrical version Doraemon: Nobita and the Ideal Land of the Sky was released in Japan yesterday (March 3rd).

It’s like Doraemon ate people.

02

More than 50 Amazon cloud games run away.

After Google shut down its cloud game platform Stadia at the beginning of this year, Amazon’s cloud game platform also suffered a blow. According to official sources, Luna, the cloud game platform that Amazon finished testing and officially launched in the United States last March, will lose more than 50 games this month, including three-year masterpieces such as Psyche, and another 35 games will leave the platform before the end of March.

According to statistics, since October last year, Amazon Luna cloud games have gradually lost 30% of the game products on the platform. It is reported that not long ago, Amazon’s cost reduction and efficiency increase actually affected the Luna cloud game department, and dozens of marketing and technical employees were laid off.

Looks like it’s going out of business, too

03

Microsoft launches all-round artificial intelligence model

IT House reported on March 4th that Bing Chat based on ChatGPT has made many users feel the power of AI, and Microsoft recently launched a more powerful all-round AI-KOSMOS-1. ChatGPT is a plain text LLM, and it is a more powerful multimodal large language model (MLLM).

Kosmos-1 can handle text, audio, images and videos, and build an all-round artificial intelligence, which can handle tasks like human thinking.

The researchers wrote in their academic papers: "As a basic component of intelligence, multimodal perception is a necessary condition to realize artificial intelligence". The visual example display model in Kosmos-1 paper analyzes the image and answers questions about the image, reads the text from the image, writes the title for the image, and tests the visual IQ with 22-26% accuracy.

This upgrade is too fast.

The popularity of ControlNet should also be discussed from this back photo.

A girl posted a back photo with three friends on the beach in a circle of friends. Very common daily sharing, photos are beautiful, but not much!

Then, a man named @viggo saw this photo, made some processing with AI painting and sent it to social software, which caused an uproar about AI painting.

Viggo used AI to process photos twice before and after painting. For the first time, he generated two comic photos with great aesthetic feeling, which changed the gloom of the original picture and made the whole picture look brand-new. The most surprising thing is that,AI did not obliterate the posture of the original picture, but greatly preserved the posture of the four girls.For example, the second girl on the left is carrying her hand behind her back, which is also preserved in the generated works.

Perhaps seeing the enthusiasm of netizens, viggo followed by a second round of creation. This time, the effect is even more amazing, no matter from the layering of the picture, the sense of lines or the use of special effects in the scene, it makes people shine.

With the popularity of his paintings, viggo shared the production method very openly. He exposed himself with the help ofStableDiffusionandControlNetThe power of.

As we all know, Stable Diffusion is a high-performance model, which generates higher quality images, runs faster, consumes less resources and occupies less memory, and is a milestone in the field of AI image generation.

01

So what is ControlNet?

A plug-in, which can accurately control and adjust the image.

ControlNet is an image morphing algorithm based on control points, which is mainly used in digital image processing, computer vision and computer graphics. In addition, it can also carry out nonlinear deformation of the image according to the given control points, so as to realize accurate control and adjustment of the image.

Let’s look at the basic structure of ControlNet first. ControlNet manipulates the input conditions of neural network blocks, thus further controlling the overall behavior of the whole neural network. here"network block"Refers to a group of neural layers, which are put together as a common unit for constructing neural networks, such as resnet block, multi-head attention block and Transformer block.

The concept is abstract, let’s take a look at its drawing effect!

1. Canny edge detection:By extracting line drawings from the original image, images with the same composition are generated.

2. Depth detection:By extracting the depth information from the original image, a map with the same depth structure can be generated.

3. ControlNet with semantic segmentation:

4. Diagram of HED edge detection

02

Where is the power of ControlNet?

-highly refined

Its advantage is that it can adjust the image with high precision without distortion.Compared with other image morphing algorithms based on grid or shape, the morphing effect of ControlNet is more natural and smooth, and it can better adapt to the characteristics of the image.

Simply put, this technology can add an additional input to the AI diffusion model and limit the output direction of AI. Just like building roads and signs in the endless desert, it provides a direction for lost travelers.

Before the advent of ControlNet, AI painters had to work hard on "magic spells" if they wanted to produce images with specific characteristics-users often needed to add a series of actions and position modifiers to describe the posture and physical characteristics of the characters in the pictures. Even so, drawing still needed a lot of luck. With ControlNet, AI can produce image files that meet specific requirements through sketches, human key point features, depth maps, human bones and other features.

At the beginning, it is mentioned that the back of four girls is generated. According to viggo, he first uses StableDiffusion pictures to convert words, then uses Text2Prompt plug-in to expand the search for keywords, and finally uses ControlNet plug-in to bind bones to start trying to change keywords.

Many people think that the release of Stable Diffusion is a milestone in the generation and development of AI painting. It provides the public with an available high-performance model, which not only produces very high-quality images, but also has low requirements for resources and memory. It doesn’t need any complicated operation, just select keywords, and it will create an image with great visual effect.

The emergence of ControlNet solved the pain point of AI painting. Using keywords to generate pictures will inevitably be flawed, especially in details.And ControlNet can improve the effect of drawing, and go deep into very subtle places.

More than that, it can also realize the conversion from line drawing to full-color drawing, and input a line drawing to get a filled drawing.

In a word, a stunning AI painting can be done by using Stable Diffusion to generate high-quality big pictures, supplemented by ControlNet icing on the cake.

Of course, its power is far more than that, besides generating static images, it can also generate dynamic videos!

03

The idea of ControlNet video

Recently, #AI One-Click magic change Video # has become one of the hot topics recently. In fact, this is the video version of ControlNet.It can generate pictures with the same composition through line drawing extraction, posture detection, or model recognition.

For example, IKUN and Titanic, which we are familiar with, can generate magic change videos with one click!

There are many ideas of videoization in ControlNet:

Method 1:Export the original video frame by frame, and then use ControlNet to transform the style of each picture. It is recognized that there is no one of the most cumbersome ways!

Method 2:Combined with EbSynth, key frames are generated by using ControlNet. Compared with the former one, it is much more convenient.

Method 3:Combining ControlNet technology with Pix2PixVideo technology, an online demonstration version of video generation supporting ControlNet is developed, which is the simplest generation method at present.

The user interface is very simple. When the original video is imported, the video will first be disassembled into a frame sequence, and the human pose map will be detected by using the Openpose model in ControlNet, and then a new portrait will be generated according to the text. Thanks to the control of the pose map, the human posture can be kept unchanged.

It can be seen that with the iteration of technology update, more and more technologies similar to ControlNet will flood into the market, and many people think that the painter profession is facing a great threat.

04

ControlNet should not let painters stop imagining.

But to help it better control the operation of the brush.

With the introduction of ControlNet in AI painting, it will bring a series of influences.This technology can help machines accomplish more tasks, improve productivity, improve painting quality and efficiency, enhance human-computer interaction, and provide new visual experience.At the same time, it also means that traditional artists may face competitive pressure.

As more and more enterprises began to use AI painting to draw images, ControlNet technology began to enter people’s field of vision. At present, many enterprises are trying to use ControlNet technology to improve their image rendering technology, and hope to gain more competitive advantages by using this technology. Applicable industries include construction industry, machinery manufacturing, energy industry, medical industry, government agencies and other industries.

It is generally believed that this can better control the "motion" of the brush and draw the desired image more accurately.

In a word, ControlNet has an important influence on the development of artificial intelligence and AI painting, but it never makes human painters lose their imagination! In the future, the development trend of ControlNet is more prospective.

Attached is the installation tutorial of ControlNet:

Premise: You should update the WebUI of AI painting to the latest version.

Pull:

The contents in https://github.com/Mikubill/sd-webui-controlnet warehouse can be pulled into the extensions folder under the WebUI file directory, or the zip can be downloaded directly.

Download:

Https://huggingface.co/lllyasviel/ControlNet/tree/main/annotator/ckpts, and put it in the ckpts directory under annotator in the plug-in directory.

Download:

The model under https://huggingface.co/webui/controlnet-modules-safetensors/tree/main is transferred to the models directory under the plug-in directory.

Now your ControlNet has been installed!

Specific use of the tutorial recommended bilibili video:

ChatGPT question and answer

ask

What are the defects of AI painting at present?

answer

Current artificial intelligence

Lack of creativity: AI painting can only generate new images based on existing images or data, lacking human creativity and imagination. Although AI can extract the features and styles of images through deep learning and generate corresponding images, AI lacks intuition, emotion and creativity, and it is difficult to create works of art with unique personality.

Unreal picture: AI painting can generate realistic images, but there are still some shortcomings in details and textures, and sometimes the generated pictures are not real enough to be easily identified.

Dependence on data: AI painting needs to rely on a large amount of data for training, and the lack of data will affect the quality of generated images. At the same time, the generated image is also easily limited by data, and it is difficult to create a new image beyond the data range.

Insufficient imitation: AI painting sometimes simply copies and repeats existing images or styles, lacking innovation and breakthrough, and it is difficult to achieve real imitation.

Insufficient ability of dialogue and interaction: At present, AI painting still lacks the ability of dialogue and interaction, so it can’t really interact and create with users, and it is difficult to meet the individual needs of users.

In the focus battle of the 27th round of Premier League, which ended on the evening of March 11th, Beijing time, Liverpool lost 0-1 away to Bournemouth, the bottom team, and the good momentum of unbeaten five rounds ended. In the last round, Liverpool beat Manchester United 7-0 at home, which once made people feel that the Red Army was finally back on track, but perhaps the last victory used up Liverpool’s good luck, but this campaign has once again returned to the previous performance of this season. In the face of Bournemouth, who won 9-0 in the first leg, Liverpool was helpless in front of the other side’s iron drum array. On the contrary, Van Dyke’s defense line was distracted again, making it easy for the opponent to counterattack the goal, and Salah, who scored a high penalty percentage, rarely kicked a penalty.

But this campaign lost to Bournemouth, and Liverpool also created a number of shameful records. First of all, Liverpool’s 7-game winning streak against Bournemouth ended, and the Premier League lost to its opponent for the second time. Second, this is the third time Liverpool have lost to the bottom team this season. The first time was 1-2 away from Manchester United in the third round, and the second time was 0-1 away from Nottingham Forest in the 13th round.

Third, Liverpool’s record in this season’s league game is 2 losses and 1 draw. Fourth, Liverpool lost to the teams at the bottom of the standings for the first time since 2011. Fifth, Liverpool lost to the lower half of the standings in the Premier League three times this season, which is the sum of the past four seasons. Sixth, Liverpool didn’t win one of the five games that kicked off at 12:30 in the Premier League this season. The record is a terrible 3 draws and 2 losses. Seventh, Liverpool played in this dizzy white away jersey in the Premier League this season, but they didn’t win a game. The record in five games is 1 draw and 4 losses.

To the regret of Red Army fans, Liverpool missed the best opportunity to return to the top four in the standings after losing to Bournemouth. In the next three Premier League matches, Liverpool will face Manchester City, Chelsea and Arsenal, and the matches with Manchester City and Chelsea will be away. Manchester City and Arsenal are in full swing, and Chelsea have regained the rhythm of winning. In addition, in the second leg of the Champions League in the middle of the week, Liverpool, which is facing the nemesis Real Madrid and unpredictable state, may suffer a five-game losing streak in the face of these four strong enemies.

1. Main features of digital intelligent factory

2. Construction scheme of digital intelligent factory

2.1. Big Database and Cloud Computing

2.2. Information system construction

2.3 Business systems (OA system, BPS system, MES system, SAP system, PLM system, parts tracing system, CRM system, QMS system, SCM system, TMS system, WMS system)

2.4 wisdom scheduling

2.5 intelligent logistics

2.6 Smart scene

2.7 Planning diagram of digital intelligent factory information system

① Intelligent energy management: real-time perception, monitoring, early warning and control of energy consumption, and real-time optimization of energy efficiency.

② Intelligent supply chain: build a network supply chain, and control and optimize the logistics, capital flow and production cycle in the supply chain system composed of suppliers, manufacturers, distributors and final customers, so as to reduce the logistics cost and shorten the production cycle.

③ Intelligent equipment: the equipment has the functions of perception, acceptance, self-discipline and intelligence.

④ Intelligent production: the deep integration of informatization and production realizes the closed-loop optimization management of all business processes at three levels: production operation, production management and management decision.

① Virtual reality (modeling and simulation technology); (One of the two major traction technologies facing the future)

② Artificial intelligence (optimization and intelligent technology): (one of the two major traction technologies facing the future)

③ Industrial intelligent robot; (one of the two major hardware)

④ Industrial network security; (one of the two major hardware)

⑤ Industrial automation; (one of the two systems)

⑥ Industrial Internet of Things; (based on the three foundations of distributed connection)

⑦ Cloud computing; (based on the three foundations of distributed connection)

⑧ Big data (cloud computing and data mining technology); (based on the three foundations of distributed connection)

Pet-name ruby visual system (one of the two systems)

Three-tier architecture of digital factory

① Data collection and analysis: collection and analysis of energy information.

② Prediction: the difference between energy efficiency bottleneck and energy consumption bottleneck.

③ Coordination and optimization: intelligent equipment coordination and optimization (intelligent) management and operation.

④ Efficiency improvement: improve energy efficiency and save energy.

Smart factory blueprint

Informatization integration of digital factory

In short, digital intelligent factory should not only realize automation, transparency, visualization and lean production process, but also realize closed-loop integration with production process in product inspection, quality inspection and analysis, production logistics and other links. Information sharing, on-time delivery and collaborative work should also be realized among multiple workshops in a factory. The construction of digital factory fully integrates information technology, advanced manufacturing technology, automation technology, communication technology and artificial intelligence technology.

(The original article was published on October 11th, by Mike Vorkunov of The Athletic website. The content of the article does not represent the translator’s point of view)

Last week, Victor Venbanyama had a very incredible moment when he led the Mets 92 team against the G League Ignition team in the United States. After receiving the ball on the right side of the arc top of Wenbanyama in the transition, he only transported the ball once and then sank to the bottom corner, hitting a drift and leaning back by three points. This talented player, who is 2.26 meters tall, has mastered the technical action of leaning back three points skillfully, without any interference from the defenders, playing like Reggie Miller at his peak.

The most surprising part is that this 18-year-old player, who is also a center with a nominal height of 2.26 meters, has perfect control over his body and everything he needs to put the ball in the basket. Through this bottom corner drift and backward three points, Wen Banyama showed his skillful skills at such a young stage and the reasons why he can become such a special talented player.

To some extent, the competition of various teams for Wenbanyama will partially define the whole new season.If Wenbanyama is really a once-in-a-century talent, then it’s not surprising that teams have tried every means to get him.Welcome to the 2022-23 season, which is a "Battle for Wenbanyama".NBA President Adam Xiao Hua said in an interview last week, "I don’t want the title of’ the next great talent’ to bring bad luck to Wenbanyama, after all, he hasn’t entered the NBA yet. But he does have all the qualities and physical talents that can really change the rules of the game. It seems that he is also eager to be a great player, standing on the big stage facing the lighting team. I know that many NBA teams are eager to get him. It’s really tempting to get Wenbanyama by lottery, but they should continue to compete hard next season. "

Nowadays, people are beginning to wonder what changes Wenbanyama will bring to a team. A simple answer is that no matter which lucky team becomes the biggest winner in the lottery and gets Wenbanyama, it will make the team look brand-new. However, each team has different degrees of talent at present, and getting Venbanya will have different degrees of influence on the speed of each team becoming a championship team or a playoff team.

Winning the No.1 pick in the lottery is not only a success in basketball, but also a surprise for the business department of the team. Superstars with global influence can promote the development of the team in all aspects, promote ticket sales, increase the sales of peripheral products, and improve the market value of the whole team.

Next, we will analyze each team that has the chance to get Venbanyama, and see what he means to each team. The order is from high to low according to the probability of each team winning the No.1 draft estimated by Tankathon website.

Reminder: The three teams with the worst record in NBA each season will have a 14% probability of winning the No.1 draft, and the probability of winning the No.1 draft is 12.5% for the team with the fourth lowest record, 10.5% for the fifth lowest record, 9% for the sixth lowest record, then 7.5% and 6% … and so on, the probability of winning the No.1 draft is 0.5% for the team with the 14th lowest record.

San Antonio

Estimated number one draft probability: 14%

Coach Povich has said many times that the Spurs’ goal in the new season is not to win the championship. Trading DeZhangtai-Murray doomed Spurs to rush to the bottom of the league in the new season. The history of the Spurs has always had good luck in lottery. In 1987, David Robinson won the No.1 lottery, and in 1997, Duncan won the No.1 lottery. These two draft picks established 20 years of success for the Spurs and won five championship trophies.

Getting Venbanama against Spurs may mean a repeat of history, bringing the team a cornerstone player to rely on. The Spurs’ current lineup already has Kelden Johnson, Sohan, primo and wasser. These young players have good long-term development prospects, but it seems that none of them has the potential to grow into a stable All-Star player. If Spurs get Venbanama, they can build a team around him that can return to the peak of team history. The past history of Spurs has proved that they know what to do. Of course, there is still a lot of room for development in Wenbanyama.

Houston rockets

Estimated number one draft probability: 14%

The Rockets already have several young players with attractive prospects. Jay Green performed strongly in the second half of his rookie season, and Shen Jing has talent and courage. Now Kevin Porter, the 30th overall pick in the first round, has shown his potential and can bring a lot of trouble to his opponents. In June this year, the Rockets just picked jabari Smith Jr. in the draft. One day, he will have the opportunity to become a tall and versatile flanker. So the Rockets actually have a good young lineup at present, with solid players in the frontcourt and backcourt.

If the Rockets get Wen Banyama again, including Kevin Porter Jr. and Shen Jing (if they agree to renew their contracts with the Rockets), the Rockets will have three potential all-star regulars at once. At the same time, the Rockets will have a lot of salary space in the offseason in 2023. With Wenbanyama, the Rockets can jump directly to the forefront of emerging strong teams.

oklahoma thunder

Estimated number one draft probability: 14%

It would be too exaggerated if Thunder won the No.1 draft. In the past three seasons, Thunder has focused on the future at the expense of the present. In the middle of every season, the Thunder will quietly turn their heads and start to rot. As a result, they gradually accumulated a lot of talented players around Alexander, including Kitty, Holmgren, Mann, Dot, Jay Williams, Pokusevski and Ji ‘an. Will all these players be famous? Maybe not, but their potential is visible to the naked eye.

As Holmgren’s injury will be fully reimbursed in the new season, Thunder can’t see this unicorn player on stage. Imagine what it would be like for Wen Banyama to appear in Thunder. Thunder can arrange a tall and long talent lineup. All positions have size advantages. Everyone on the court can shoot, dribble and create offensive opportunities, and there are two monster-level basket guards. Getting the Venbanya Horse will make the general manager Presti’s plan a great success, and further promote the league’s protest against the team’s ruin.

Indiana pacers

Estimated number one draft probability: 12.5%

The Pacers are still in an awkward position. halliburton is going to take over the team. Rookie Marcelin is ready to fight alongside him, while the Pacers are still peddling Hilde and Turner. Pacers have never won the No.1 draft in history, and next year may be their first time. The lineup built with halliburton and Wenbanyama as the core can give the Pacers a major advantage in the position of point guard and center. Marcelin can tap his potential in the flank position. Duarte and Isaiah Jackson may also be long-term starters of the team. All this is a very, very good start for the Pacers, increasing their exposure in the national live broadcast. Only one game of the new Pacers is scheduled to be broadcast live in the United States, and there are only five games in the 2021-22 season. If the Pacers can get the Venbanyama, at least there will be a qualitative leap in the number of live games in the United States.

Utah jazz

Estimated number one draft probability: 10.5%

It would be nice if the Jazz could get Venbanyama, for which they paid almost everything. I sent away two All-Star players and three starters just to spoil the competition for Wimbanya. However, Wen Banyama’s situation is not so ideal. He is surrounded by some young players with uncertain future or some veterans who will be traded at any time. At present, there is no better way to promote reconstruction than getting Venbanya Ma, but this jazz team that started from scratch still needs to add many talented teams around him. On the positive side, the Jazz have piles of future draft picks, and have the ability and confidence to push forward the process of reconstruction in a leisurely manner. Or, when needed, they can stud these draft assets to build a competitive team around Wenbanyama.

Orlando magic

Estimated number one draft probability: 9%

If Magic wins the No.1 draft, it will be the second time in the history of their team that they have won the No.1 draft for two consecutive years. The last time was in 1992 and 1993. In 1993, Magic won the No.1 draft with a 1.5% probability (the lowest in history), and Chris Webber was selected. No shortage of inside magic sent Webber to the Warriors in exchange for the flower show "Penny" Fanny Hardaway, and Magic entered the finals under the leadership of No.1 champion Lang O ‘Neill and Penny Hardaway in 1992. The 2.08-meter-tall Bankairo has the potential to be the fulcrum of the magic offensive end, and has the outside skills to create opportunities for himself and his teammates. Flange player Franz Wagner performed strongly in his rookie season. Sagues’s career was unstable at the beginning, but there is still potential to be developed. Wendell Carter and Fultz will be a good lineup puzzle. The future of Bamba and Isaac is uncertain.

If Magic get Venbanyama, they may have a group of super-sized skilled players. It’s incredible. Imagine the picture of Benkairo playing with Wenbanyama, with Sagues and Wagner standing in the bottom corner. Or Sagues is chasing the opponent’s attack point, and the picture of Wenbanyama falling in the inside basket is one of the most interesting endings when Wenbanyama goes to magic.

Detroit piston

Estimated number one draft probability: 7.5%

The piston’s upper limit may be the highest after getting Wenbanyama. Cunningham already looks like the best linebacker in the future, and Ivey may be selected as an All-Star. Looking back on this year’s draft, it’s amazing that Ivey can fall to the fifth overall pick. Sadik Bay has scored 50+ in a single game this season, and is an ideal flank player who is good at shooting. Durham’s new season can prove that he deserves an NBA starting center position, but he certainly won’t be a reason to give up Wimbanya. As for Turta, he is a big bully.

With the help of Cunningham and Venbanyama, the Pistons will have two star players in the next few years, avoiding the long and painful process of finding top star partners with only one star. On the basis of the existing lineup, the pistons naturally have the property that both small balls and big balls can be played, so they can not only fight hard inside, but also open up space to take the technical flow. If Cunningham is only the second best player in the Pistons in the next four years, what a luxury it would be.

Sacramento king

Estimated number one draft probability: 6%

If the king wins the No.1 draft, it’s probably a comfort to them for nearly 20 years, and a late reward is better than nothing. King already has a good core squad, and Wenbanyama can raise the upper limit of the current squad a lot. He can adapt to any player.

Wizards of Washington

Estimated number one draft probability: 4.5%

Even if Wizards get Wimbledon, do you think they can win more than 50 games in a season? Since the 1978-79 season, the Wizards have never won more than 50 games in a single season. However, if we can get Wenbanyama, it will be of great help to the Wizards, a team whose development has stagnated in the past few seasons. The arrival of Bunyama will enable the Wizards to make the best use of the remaining peak period of Bill’s career, and the Wizards already have some interesting talented young people, such as Ba Cun Jian, Afdia, Johnny Davis, and some experienced players like Porzingis and Kuzma. Porgis can tell Wenbanyama what kind of danger a 2.21m big man will face in the NBA. Of course, as an NBA official, I definitely hope that a potential championship team will emerge in Washington, the capital of the United States.

Charlotte wasp

Estimated number one draft probability: 3%

For NBA and team owners, there is an interesting question: Do they prefer to raise the market valuation of the strong team or the weak team among the 30 teams? According to the data of Sportico website, the market value of Hornets ranks fourth from the bottom among all NBA teams. Perhaps international talent stars like Wen Banyama can help Hornets a lot in this respect. We’ve seen this before. According to the data of Forbes.com, Bucks ranked the bottom of the league in market valuation in 2013. A few months later, they chose Brother Alphabet, and now Bucks’ market valuation has climbed to 17th place. It will be interesting to blend with the Hornets on the court. Lamelo-Bauer is an expert in passing, and Wenbanyama will get a lot of empty catches when he plays three balls. They will become the cornerstone partners of the Hornets.

New york Knicks

Estimated number one draft probability: 2%

Even assuming that the Knicks can win the No.1 draft, it will annoy many Knicks fans, who will remind you angrily that the Knicks have never taken advantage of the lottery, let alone won the No.1 draft. But let’s be bold. After all, the Knicks did win the No.1 draft before, and the prize was a center who could change the whole league. The Knicks can do it again. Wenbanyama is a panacea to solve all the needs of the Knicks. Since trading Anthony, the Knicks have never had a star who can be selected into the best lineup, and this summer they missed Mitchell. In the past 20 years, the Knicks have not been able to attract other stars except Anthony. At present, the Knicks have Barrett and some other excellent and young role players, while the team still has many draft assets to acquire more talented players. The Knicks will be more willing to use these picks and young players to change stars if they get Wenbanyama. They know which players can really help.

Portland

Estimated number one draft probability: 1.5%

It will definitely be interesting for Bunyama to go to the Blazers. Lillard continues to lead the Blazers after a year of lineup reorganization. There was a rumor that Lillard might leave, but now it seems that he will stay in the Blazers for several years. The 23-year-old Ampheni Simmons is a reliable partner in the backcourt of Lillard, who has the ability to score continuously. Sharp, the rookie selected by the team this summer, also looks quite good. Beside Lillard, the opponent’s defensive focus, Wenbanyama not only has a great veteran role model to learn from, but also provides a lot of buffer space for him to adapt to the strength of NBA. The Blazers already have enough talent, and the arrival of Wenbanyama can make the Blazers a perennial playoff team in the West almost immediately. As for the higher level, it depends on the growth rate of Wenbanyama and how long Lillard can keep its peak.

Chicago Bulls

Estimated number one draft probability: 1%

From a business point of view, going to the Bulls is an ideal result for both NBA and Wimbledon. As a team with a long history and a huge market, the Bulls jerseys of Wenbanyama will be snapped up on the first day he joined the Bulls. As for the situation on the court, it’s hard to say. Demar derozan has played well with the Bulls this season, but he is 34 years old. The new season will be the last year of his contract. Raven will be a good partner for Wimbledon, Vucevic will become a free agent next summer, and it’s hard to say the situation of Lanzo Ball and Patrick Williams. Nevertheless, the Bulls with Raven, caruso and Healthy Ball, plus Wenbanyama, have a lot to watch, and the lineup around Wenbanyama also has some flexibility.

New Orleans Pelican